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Donor Histocompatibility Form

UNOS/OPTN histocompatibility · UNOS / OPTN

Tissue typing and compatibility data for organ matching submitted by the histocompatibility laboratory.

Form Details

Total fields
60
Auto-fillable
30 (50%)
Time without BeneFill
45 minutes
Time with BeneFill
12 minutes
Time saved
33 minutes
Filled by
doctor
Frequency
per incident

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Where to Submit This Form

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Completed at the histocompatibility/tissue typing laboratory

Testing is ordered by the transplant center and performed at an accredited HLA laboratory.

Required Attachments

  • 📎 Blood samples for HLA typing and crossmatch testing
  • 📎 Completed laboratory requisition from the transplant center
  • 📎 Patient and donor demographic information
  • 📎 Prior HLA typing results (if available)

Processing Time

HLA typing: 1-3 business days. Crossmatch testing: 4-6 hours (virtual crossmatch may be faster). Comprehensive compatibility assessment: 1-2 weeks.

What Happens Next

Results are reported to the transplant team, who use them to determine donor-recipient compatibility. For deceased donor organs, results are available in real-time through the UNOS system.

Tips for This Form

  • Living donors undergo extensive compatibility testing before a transplant can proceed
  • High PRA (Panel Reactive Antibody) levels may make it harder to find a compatible donor — discuss desensitization options with your team
  • Virtual crossmatch technology has significantly sped up the deceased-donor allocation process
  • If you have been sensitized through prior transplants, transfusions, or pregnancies, inform your team

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